Luckey et al., 2025(The Lancet): An international, randomised, controlled, open-label, phase 3, non-inferiority clinical trial was conducted. The study evaluated the efficacy and safety of zoliflodacin versus ceftriaxone plus azithromycin in patients aged 12 years and older with clinical suspicion of uncomplicated urogenital gonorrhoea. Eligible participants were randomly assigned (2:1) […]
Zhang et al 2026 (JAMA): A large long-term study followed over 131,821 people from Nurses’ Health Study and the Health Professionals for up to 43 years to examine whether drinking coffee or tea affects the risk of dementia. During the study 11,033 develop dementia. Study revealed that higher caffeinated coffee […]
Luciano et al., 2025 (N Engl J Med): A randomized, double-blind, placebo-controlled trial of shunt surgery was conducted among 99 participants having idiopathic normal pressure hydrocephalus (iNPH). It was observed that shunt surgery increases the gait velocity and was found unchanged in the placebo. A significant difference favoring shunt surgery […]
Estrella et al 2025(JAMA): A Meta-Analysis of 821327 outpatient participants and nearly 39 639 hospitalized patients who had both creatinine and cystatin C based eGFR measurements were conducted. Participants were followed for an average of 11 years to evaluate long term outcomes. The analysis showed that approximately 11% of outpatients and […]
Wharton et al., 2025 (N Engl J Med): In a phase 3 multinational, randomized, double-blind trial, Orforglipron, a small-molecule, nonpeptide GLP-1 receptor agonist, was investigated as a treatment for obesity. The safety and efficacy of orforglipron at doses (mg) of 6, 12, or 36 once-daily, as compared with placebo (assigned […]
Drug development refers to the process of bringing a new drug molecule into the market through preclinical and clinical practice. It requires substantial investments in terms of capital (∼$2.2 billion), human resources, research skills, and technological expertise. The process of drug development can be broadly classified into preclinical and clinical studies. The […]
HEOR : In the ever-evolving healthcare landscape, the field of Health Economics and Outcomes Research (HEOR) has emerged as a crucial discipline to bridge the gap between clinical trials and real-world healthcare outcomes. While clinical trials provide essential data on the efficacy of medical treatments, they often fall short of […]
CRF Designing : Case Report Form (CRF), as defined by the ICH Good Clinical Practice (GCP) guidelines, is a printed, optical, or electronic document used by clinical professionals to accurately capture all protocol-required data for each participant enrolled in a clinical trial. This data is later reported to the sponsor. […]
Regulatory Medical writing has globally become an essential tool for generating authenticated documents related to products undergoing clinical trials. The principle of regulatory medical writing is to provide high-quality scientific documentation tailored to the needs of the target audience. Currently, the field has grown more complex due to evolving regulatory […]
Medical communication is an essential component of modern healthcare, bridging the gap between complex scientific data and practical understanding for healthcare professionals, patients, and stakeholders. In clinical trials, where accuracy and protocol are paramount, success is also dependent on how effectively information is conveyed. Whether through educational tools, regulatory submissions, […]