Higher caffeinated coffee intake is significantly associated with lower risk of dementia

Zhang et al 2026 (JAMA): A large long-term study followed over 131,821 people from Nurses’ Health Study and the Health Professionals for up to 43 years to examine whether drinking coffee or tea affects the risk of dementia. During the study 11,033 develop dementia. Study revealed that higher caffeinated coffee intake was significantly associated with lower dementia risk and lower prevalence of subjective cognitive decline. In the Nurses’ Health Study cohort, higher caffeinated coffee intake was also associated with better objective cognitive performance, although the association with global cognition was not statistically significant. Tea intake showed similar associations, whereas decaffeinated coffee intake was not associated with lower dementia risk or improved cognitive performance. Dose-response analysis indicated the most pronounced differences at approximately 2–3 cups of caffeinated coffee per day or 1–2 cups of tea per day. Overall moderate intake of Caffeinated Coffee and tea was linked to a lower risk of dementia and slightly better cognitive function.